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Oral & Craniofacial Tissue Engineering

Edited by Ole T. Jensen, DDS, MS

Official Journal of the Tissue Engineering Society, the Chinese Society of Oral Biomedicine, and the Japanese Society of Regenerative Medicine

ISSN (print) 2158-3722 • ISSN (online) 2158-3706

Oral & Craniofacial Tissue Engineering
Winter 2011
Volume 1 , Issue 4

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Transcription Factors for Dental Stem Cell Differentiation

Sandra Viale-Bouroncle, MSc/Oliver Felthaus, Dipl Biol/Gottfried Schmalz, DDS, Dr med dent, PhD/Torsten E. Reichert, DDS, DMD, PhD, MD, Dr med, Dr med dent/Christian Morsczeck, Dipl Biol, Dr rer nat (PhD)

Pages: 306314

Dental stem cells are excellent for oral and craniofacial tissue engineering. A profound knowledge about molecular processes in dental stem cells is necessary to create treatment approaches in oral medicine. Transcription factors regulate gene expression and provide decisive information for cellular functions. In recent years, the authors have investigated transcriptomes in dental stem cells before and after osteogenic differentiation. The present paper reports on the potential role of selected transcription factors, including ZBTB16, TP53, and SP1, in dental stem cell differentiation. This review discusses putative molecular processes in dental stem cells and summarizes the current knowledge. Oral Craniofac Tissue Eng 2011;1:306314

Key words: dental stem cells, differentiation, molecular biology, transcription factors

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