Home Subscription Services
 
   

 
Journal of Laser Applications
Jola Home Page
About the Editor
Editorial Board
Author Guidelines
Submission Form
Reprints / Articles
Permissions
Advertising
MEDLINE Search
 
 
 
 
 
FacebookTwitter
Quintessence Publishing: Journals: JOLA

 

The Journal of Oral Laser Applications

Edited by Prof Dr Andreas Moritz and Prof G. Lynn Powell

Official publication of the European Society for Oral Laser Applications

ISSN (print) 1473-7809 • ISSN (online) 1867-5611

Publication:
JOLA
Winter 2005
Volume 5 , Issue 4

Pages: 231-235
Back
Share Abstract:

Low-intensitiy Laser Therapy in the Treatment of Mucositis Induced by Chemotherapy and Radiotherapy

Kühn, Alessandra/Wagner, Joao Carlos B./Brunetto, Algemir Lunardi/Volkweis, Maurício R./Dall`Magro, Eduardo

Purpose: The aim of this article was to develop a protocol for the treatment of oral mucositis induced by chemotherapy and radiotherapy. A pilot trial was conducted with low-intensity laser therapy (GaAlAs/InGaAlP laser) to decrease the lesions’ manifestation time and to promote pain control. Materials and Methods: Fifty patients for whom chemotherapy or chemoradiotherapy was indicated were evaluated in this study. Fifteen patients developed mucositis (30%) and were divided into 3 groups of 5, receiving lowintensitity laser therapy 3 times a week, with a specific dosage in each group. Group A: GaAlAs laser, wavelength 830 nm (infrared), power 70 mW, dose 5 J/cm2; group B: InGaAlP Laser, wavelength 685 nm (red), power 35 mW, dose 5 J/cm2; group C: placebo. The presence and severity of mucositis was clinically evaluated using the WHO scale, and pain was measured by using a visual analogue scale (VAS). The Kruskal-Wallis test was used to test differences among groups. Results were considered statically significant when p < 0.05. Results: The infrared laser 830 nm (Group A) showed therapeutic superiority when compared with the red laser 685 nm (Group B) and the Group C (placebo). Group B showed intermediate results between groups A and C in terms of mucositis duration and the decrease of the lesion grade at 7 and 15 days. However, the pain level after 7 days of the treatment continued to be high compared to Group C (placebo). Conclusions: Low-intensity laser therapy with a 830-nm (infrared) wavelength can be indicated for oral mucositis induced by chemoradiotherapy, due to its better therapy results compared to the red laser (685 nm) and the placebo group in the same application periods.

Keywords: low-intensity laser therapy, oral mucositis, chemotherapy, radiotherapy

Full Text PDF File | Order Article

 

 
  © 2014 Quintessence Publishing Co Inc
 

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog