Lipoid proteinosis is a rare syndrome with autosomal recessive inheritance. This disease is characterized by diffuse deposition of hyaline substance in the dermis, the submucosal connective tissue and various internal organs. The patient chosen for the case study was a 21-year-old female. After biopsy with a scalpel, bleeding was seen in some areas and suturing was very difficult. Nd:YAG and Er:YAG laser were used for biopsy of the oral lesion, and after laser treatment, there was only slight bleeding, eliminating the need for suturing. The healing process after treatment proceeded unremarkably. As suturing is difficult in these patients and mucosa is rigid, the use of lasers offers some advantages for biopsy and reshaping of oral lesions in this syndrome.
Keywords: Nd:YAG, Er:YAG, laser, lipoid proteinosis, biopsy, syndrome