The reliability and failure modes of molar crowns supported by three different implant-supported designs were tested according to the following groups: group 1, one standard-diameter implant (3.75 mm); group 2, one narrow-diameter implant (3 mm); and group 3, two narrow-diameter implants (3 mm). Loads were applied as mouth-motion cycles using a step-stress accelerated life-testing method. β values for groups 1 and 3 (1.57 and 2.48, respectively) indicated that fatigue accelerated the failure of both groups, but not for group 2 (0.39). Abutment screw failure was the chief failure mode. Strength and reliability were significantly higher for groups 1 and 3 compared to group 2. Int J Prosthodont 2011;24:557–561.