LOGIN
 
Share Page:
Back

Volume 16 , Issue 2
March/April 2003

Pages 141144


Cytotoxicity of Antimicrobial Tissue Conditioners Containing Silver-Zeolite

Yasuhiko Abe, DDS, PhD, Morikatsu Ueshige, DDS, PhD, Maho Takeuchi, DDS, Mie Ishii, DDS, PhD, Yasumasa Akagawa, DDS, PhD


PMID: 12737244

Purpose: The purpose of this study was to determine the effects of incorporating antimicrobial silver-zeolite on the in vitro cytotoxicities of five tissue conditioners against the living dermal model, which consisted of normal human dermal fibroblasts in a collagen lattice. Materials and Methods: Samples of each tissue conditioner containing silver-zeolite (2 wt% and 5 wt%) were prepared; samples without silver-zeolite were used as a control. Cytotoxicity of each sample against the living dermal model was evaluated by cell viability with MTT assay. Results: Cell viabilities for Visco-Gel, GC Soft-Liner, FITT, and SR-Ivoseal decreased with increasing silver-zeolite content. Cell viability for Shofu Tissue Conditioner showed no significant difference with degree of silver-zeolite incorporation and had higher values than other tissue conditioners. Conclusion: Individual compounds eluted from tissue conditioners and silver ions released from silver-zeolite might cause such cytotoxicity. The results suggest that Shofu Tissue Conditioner is a possible candidate for a novel antimicrobial tissue conditioner containing silver-zeolite because it showed the highest cell viability and the smallest influence of incorporating silver-zeolite. Int J Prosthodont 2003;16:141144.


Full Text PDF File | Order Article

 

 
Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.

 

© 2017 Quintessence Publishing Co, Inc

IJP Home
Current Issue
Ahead of Print
Archive
Author Guidelines
About
Accepted Manuscripts
Submission Form
Submit
Reprints
Permission
Advertising
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us
Help