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Volume 5 , Issue 6
November/December 1992

Pages 558-562


The Cytotoxic Effects of Denture Base Resin Sealants

Lefebvre/Schuster/Richardson/Barron


PMID: 1307016

Previous studies have shown that light-polymerized denture base resins have a cytotoxic effect on oral epithelial cells. The purpose of this in vitro study was to examine the effects of two denture base resin sealants when used on three light-polymerized denture base resins. Sample disks were examined for their effect on protein synthesis. Results indicate that one sealant protected the cells against toxic effects of the materials (P < .05), while one sealant enhanced toxicity up to 88% above that attributed to the resin alone.


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