LOGIN
 
Share Page:
Back

Volume 12 , Issue 2
March/April 1999

Pages 153-159


A Review of In Vitro and In Vivo Methods to Evaluate the Efficacy of Denture Cleansers

Nikawa/Hamada/Yamashiro/Kumagai


PMID: 10371918

Purpose: This review summarizes the methods employed to evaluate denture cleansers and makes some suggestions on the methodology of evaluation. Materials and Methods: More than 20 articles evaluating the efficacy of denture cleansers were compared, and the advantages and disadvantages of each method were evaluated. Results: The results obtained vary depending on the methods used to evaluate the efficacy of denture cleansers, particularly among in vitro and in vivo assays. In addition, it is pointed out that chemical denture cleansers are not as efficacious in clinical use as in the in vitro assay. The uncertainty over efficacy may be caused by nonstandardized methodology and reports of conflicting results. Conclusion: A standardization of the methodology is needed. This should include evaluation of the efficacy of cleansers through both in vivo and in vitro assay methods; standardization of the materials and methods used in studying the efficacy of denture-cleansing regimens; and the examination of not only selected microorganisms from limited surface areas of a denture, but the microorganisms in denture plaque from the whole surface of a denture. It would also be preferable to use methods and/or media that make it possible to not only qualify but also quantify the microbial plaque.


Full Text PDF File | Order Article

 

 
Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.

 

© 2017 Quintessence Publishing Co, Inc

IJP Home
Current Issue
Ahead of Print
Archive
Author Guidelines
About
Accepted Manuscripts
Submission Form
Submit
Reprints
Permission
Advertising
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us
Help