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Volume 20 , Issue 5
September/October 2007

Pages 504506

Susceptibility of Candida Isolates from Denture-Related Stomatitis to Antifungal Agents In Vitro

Barbara Dorocka-Bobkowska, MD, DDS, PhD / Krystyna Konopka, MD, PhD

PMID: 17944341

The aim of this study was to determine the susceptibility of Candida isolates obtained from patients with Candida-associated denture stomatitis to 4 antimycotics. Antifungal susceptibility was assayed using the ATB-Fungus-2INT test. A total of 120 Candida strains were identified: C albicans (59.2%), C glabrata (20%), C tropicalis (12.5%), and C parapsilosis (8.3%). Amphotericin B, 5-fluorocytosine, fluconazole, and itraconazole were effective against 100%, 98.6%, 88.7%, and 87.3% of C albicans and 79.6%, 77.6%, 71.4%, and 79.6% of the other Candida strains, respectively. The identification of candidal strains and determination of their susceptibility to antifungals may improve the management of Candida-associated denture stomatitis. Int J Prosthodont 2007;20:504506.

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