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The International Journal of Prosthodontics

Edited by George A. Zarb, BChD, DDS, MS, MS, FRCD(C)

ISSN 0893-2174

September/October 2006
Volume 19 , Issue 5

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Bone Formation Around Immediately Placed Oral Implants In Diabetic Rats

Yih-Chuen Shyng, PhD, DDS / Hugh Devlin, PhD, MSc, BSc, BDSb/Keng-Liang Ou, PhD

Pages: 513514
PMID: 17323732

Research has shown a decrease in femoral bone-to-implant contact in rats with uncontrolled diabetes. The present study aimed to test the hypothesis that this decrease may be the result of a decreased mineral apposition rate. In 20 normal and 20 diabetic rats, a titanium implant was inserted into the tooth extraction socket immediately after the right maxillary molars were extracted. There was a significantly reduced mineral apposition rate in the diabetic rats compared with the normal rats (P = .0001), but no difference between rats sacrificed at 20 and 40 days (P = .297). The results suggest that implant insertion immediately following tooth extraction in patients with poorly controlled diabetes is contraindicated. Int J Prosthodont 2006;19:513514

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