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ENDO - Endodontic Practice Today

Edited by Bun San Chong and Edgar Schäfer

Official Publication of the Belgian Association for Endodontology and Traumatology (BAET) and the French Society of Endodontics (SFE)

ISSN (print) 1753-2809 • ISSN (online) 1753-2817


Spring 2013
Volume 7 , Issue 1

Pages: 47-51
Share Abstract:

Comparative antimicrobial and antifungal efficacy of BioPure MTAD, Metapex and aztreonam on Enterococcus faecalis and Candida albicans

Balakrishnan, Rajkumar / Dhole, Tapan Kumar / Dubey, Sandeep / Boruah, Lalit Chandra / Langde, Sushil P.

Aim: This study was undertaken to determine the antimicrobial and antifungal effect of BioPure MTAD, Metapex and aztreonam against Enterococcus faecalis and Candida albicans.
Materials and method: The testing of the antimicrobial and antifungal efficacy of selected medicaments against Enterococcus faecalis and Candida albicans was done by the agar disc-diffusion method. Pre-sterilised Whatman paper discs, 6 mm in diameter and soaked with the test solution, were prepared and placed onto the previously seeded agar petri plates. Each plate was incubated at 37°C for 48 hours. A zone of inhibition was recorded for each plate and the results were analysed statistically. Saline and ethanol were used as control groups in this study.
Results: BioPure MTAD was effective against all the test microorganisms with a substantial zone of inhibition. Saline and ethanol used as controls were ineffective. Metapex and aztreonam showed a significantly larger average zone of inhibition against E. faecalis, but were not effective against C. albicans.
Conclusions: BioPure MTAD was found to be superior in its antimicrobial and antifungal abilities compared with the other irrigants used. When Metapex and aztreonam were compared, Metapex showed a greater antimicrobial effect, but both failed to show any antifungal effect.

Keywords: aztreonam, Biopure MTAD, C. albicans, E. faecalis, Metapex

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