Home Subscription Services
 
   

 
Endodontic Practice Today
ENDO Home Page
About the Editor
Editorial Board
Submit
Author Guidelines
Submission Form
Reprints / Articles
Permissions
Advertising
MEDLINE Search
Official Site
 
 
 
 
 
FacebookTwitter
Quintessence Publishing: Journals: ENDO

 

ENDO - Endodontic Practice Today

Edited by Antionio Bonaccorso, Bun San Chong, Edgar Schafer, and Luc van der Sluis

Official Publication of the Belgian Association for Endodontology and Traumatology (BAET), the French Society of Endodontics (SFE) and the Norwegian Endodontic Society (NEF)

ISSN (print) 1753-2809 • ISSN (online) 1753-2817

Publication:

Summer 2012
Volume 6 , Issue 2



Pages: 105 - 112
Back
Share Abstract:

Tissue engineering and its application in endodontics: an overview

Loomba, Kapil / Bains, Rhythm / Bains, Vivek Kumar / Loomba, Anju / Nadig, Roopa R. / Shrivastava, Tarun V.

Aim: To gain an overview of the basic concept of tissue engineering, which helps in understanding its potential application and scope in the field of clinical endodontic practice. Summary: The accepted use of regenerative therapy in the field of endodontics can be designed to restore and replace lost dentine, pulp, cementum and periodontal tissues. The key elements of tissue engineering are the stem cells or units, the signals or growth factors/morphogens (GFs), and a carrier or scaffold of extracellular matrix. The dental pulp has been identified as a source of mesenchymal stem cells, which by definition are adult multipotent stem cells that are capable of differentiating into mesenchymal and non-mesenchymal tissues, such as fat, bone, cartilage and neural cells. The pulp from extracted third molars, teeth extracted for orthodontic or periodontal reasons or supernumerary teeth offer a valuable source of stem cells for research. Autologous dental pulp stem cells may be frequently used for pulp regeneration. Induced pluripotent stem cells, which are artificially derived through stem cell gene transfer into an adult stem cell, may have the potential to be utilised as an alternative source for autologous pulp tissue regeneration. Keywords: adult stem cells, dental pulp, regeneration, root canal therapy, tissue engineering

Full Text PDF File | Order Article

 

 
  © 2014 Quintessence Publishing Co Inc
 

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog