Home Subscription Services
 
   

 
The Journal of Adhesive Dentistry
EJED Home Page
About the Editor
Editorial Board
Submit
Author Guidelines
Submission Form
Reprints / Articles
Permissions
Advertising
MEDLINE Search
Official Site
 
 
 
 
 
FacebookTwitter
Quintessence Publishing: Journals: EJOI

 

European Journal of Oral Implantology

Editor in Chief: Dr. Marco Esposito

Official publication of the British Society of Oral Implantology (BSOI) and the Dutch Society of Oral Implantology (NVOI)

ISSN (print) 1756-2406 • ISSN (online) 1756-2414

Publication:

Spring 2008
Volume 1 , Issue 1

Back
Share Abstract:

Efficacy of prophylactic antibiotics for dental implants: a multicentre placebo-controlled randomised clinical trial

Esposito, Marco/Cannizzaro, Gioacchino/Bozzoli, Paolo/Consolo, Ugo/Felice, Pietro/Ferri, Vittorio/Landriani, Stefano/Leone, Michele/Magliano, Antonio/Pellitteri, Guiseppe/Todisco, Marzio/Torchio, Cinzia

Purpose: To evaluate the efficacy of prophylactic antibiotics for dental implant placement. Materials and methods: Twelve Italian private practices agreed to participate in this trial, each centre providing 30 patients. One hour prior to implant placement, patients were randomised, for consumption orally of 2 g amoxicillin or identical placebo tablets. Patients needing bone augmentation procedures were not included. Outcome measures were prosthesis and implant failures, adverse events and post-operative biological complications. Patients were seen 1 week, 2 weeks and 4 months post-operatively. Results: One centre did not deliver any data and 14 patients had to be excluded from the trial for various reasons. One hundred and fifty-eight patients were evaluated in each group and none dropped out at 4 months. Two prostheses and two implants failed in the antibiotics group, compared with four prostheses and nine implants in the placebo group. There were no statistically significant differences for prosthesis failures, implant losses, complications and side effects. Conclusions: No statistically significant differences were observed. However, four times more patients in the placebo group experienced implant failures than in the antibiotic group, and this requires further investigation.

Keywords: amoxicillin, antibiotic prophylaxis, dental implants, multicentre randomised placebo-controlled clinical trial

Full Text PDF File | Order Article

 

 
  © 2014 Quintessence Publishing Co Inc
 

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog