Objective: To study the effect of intraoral sandblasting on the bond strength between Ni-Cr alloy and composite resin. Methods: Twelve Ni-Cr alloy cylindrical samples were fabricated and divided into two subgroups. Experimental group was sandblasted with 30-µm Al₂O₃ particles and the control group was not sandblasted. The metal surfaces were treated with alloy primer, then bonded to composite resin cylinders using Voco Cimara system (Germany) and stored in 37°C distilled water for 24 h, this was then subjected to shear force in a universal testing machine at a crosshead speed of 1 mm/min. Stress at failure was calculated in MPa, and the mode of failure was recorded. The Student t test was applied to analyze data. Result: The shear bond strength of experimental group is significantly higher than the control group. All the adhesive failure happened at the Ni-Cr alloy and composite resin interface. Conclusion: Intraoral sandblasting could significantly enhance the bond strength between the Ni-Cr alloy and composite resin.