Home Subscription Services
 
   

 
The Chinese Journal of Dental Research
About the Editor
Editorial Board
Author Guidelines
Submission Form
Reprints / Articles
Permissions
Advertising
MEDLINE Search
Official Site
 
 
 
 
 
FacebookTwitterYouTube

Publication:
The Chinese Journal of Dental Research

Year 2003
Volume 6 , Issue 4

Back
Pages: 26 - 28

Microinjection of Penicillin G-K into Arachnoid Space at Obex on Concentration of 5-HT and Substance P in Brain Stem

Yingxian Fan/Hongchen Sun/Hongjuan Liu/Yonghua Al

Objective: To investigate the changes in 5-HT and substance P in the brain stem of rats with trigeminal neuralgia. Materials and Methods: The animal model of trigeminal neuralgia in rats was established and then measured the concentration of 5-HT and substance P using fluorophotometry and radioimmunological analysis. Results: The concentration of 5-HT in the experimental group was significantly lower than in the normal group (p<0.01). The concentration of substance P in the experimental group was much higher than in control group. Conclusion: The concentration of 5-HT in brain stem was significantly lower in trigeminal neuralgia, while substance P may mediate conduction of nociceptive signals from trigeminal neuralgia.

 

 

  © 2014 Quintessence Publishing Co Inc
 

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog