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The Chinese Journal of Dental Research

Year 2003
Volume 6 , Issue 2

Pages: 43 - 46

Effect of a Dentifrice Containing Triclosan and Sodium Monofluorophosphate on Dental Plaque and Salivary Mutans Streptococci Levels in Shanghai Schoolchildren Aged 12-13 Years

Sizhen Shi, Daniel J. Caplan, Qin Liang, Shigeru Nagashima, Toshiyuki Tanaka, Naoko Takase, John W. Stamm

Objective: To evaluate the efficacy of a new dentifrice containing 0.3% triclosan and 1.1% sodium monofluorophosphate. Material and Methods: The randomized clinical trial was conducted over a six-month period and involved 239 Shanghai schoolchildren aged 12-13 years. Dental plaque development and the salivary Mutans streptococci (MS) levels were examined at baseline, after 3 months, and after 6 months. Results: The efficacy of the test dentifrice on the reduction of plaque formation differed significantly from a placebo dentifrice at 3 months and at 6 months. The test dentifrice had had no significant effect, relative to the placebo, in reducing the children’s salivary MS level, but had greatly decreased salivary MS levels in both the test and the placebo groups. Conclusion: The new dentifrice containing 0.3% triclosan and 1.1% SMFP may have substantial potential to achieve dental plaque reduction.



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