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Publication:
The Chinese Journal of Dental Research

Year 2003
Volume 6 , Issue 1

Back
Pages: 69 - 72

Retention of Lactic Acid in Dental Plaque in Relation to an Invididual’s Susceptibility to Dental Caries

Zuhua Wang/Xuejun Gao/Yuqin Li

Objective: To study the content of lactic acid in dental plaque after sucrose challenges in relation with an individual’s susceptibility to dental caries. Methods: Subjects were grouped as rampant-caries (RC) group: 22; DMFT >/= 15; caries-positive (CP) group: 15, DMFT >/= 10; caries-free (CF) group: 18, DMFT = 0. Plaque samples were separately collected before, and 7, 15, and 30 mins after a 10% sucrose rinse. Plaque fluids were isolated by centrifugations. The compositions in plaque fluid including lactic acid and other organic acids were analyzed by the capillary electrophoresis method. Results: Before a sucrose rinse, the contents of lactic acid in plaque fluids among the three groups were not significantly different. Within 30 mins after the sucrose rinse, the contents of lactic acid in the rampant-caries group were significantly higher than those in the caries-free group (14.61 ± 5.60 mmol/L compared with 4.08 ± 2.36 mmol/L at 30 min after the rinse, p < 0.05). Conclusions: Retention of lactic acid in dental plaque after sucrose challenges may be a key issue in relation to caries susceptibility.

 

 

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