Objective: To investigate the effect of tea polyphenols (TP) on the adherence of main cariogenic bacteria to salivary acquired pellicle or collagen and reveal the anticarious mechanisms of TP further. Methods: In vitro models of experimental pellicle S-HA and C-HA were formed by immersing the hydroxyapatites in saliva or collagen I solution respectively. Streptococcus mutans, Actinomyces viscosus and Lactobacillus were chosen as the main cariogenic bacteria, and adherence tests were taken with TP-treated S-HA/C-HA or bacteria. Results: In both parts of this study, TP solution, the concentration of which was within 1 to 4 mg/mL, could inhibit not only the attachments of S mutans and A viscosus to S-HA, but also the adherence of all three types of bacteria to C-HA effectively, and the inhibition rates rose with the increase of the concentration of TP solution. Conclusions: Tea polyphenols can inhibit the adherence of main cariogenic bacteria to salivary acquired pellicle and collagen effectively.
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