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Publication:
The Chinese Journal of Dental Research

Year 2001
Volume 4 , Issue 1

Back
Pages: 47 - 51

Risk Ratio of Genetic Factors in Recurrent Aphthous Ulcer

Xi Jui Guo, DDS/Xing Chao Ruan, BSD

Objective: To study the relationship of sister chromatid exchange, micronucleus rate, and chromosome structural aberration rate of lymphocytes in recurrent apthous ulcer patients. Methods: Sister chromatid exchange, micronucleus rate, and chromosome structural aberration of 60 recurrent apthous ulcer patients were determined, and were analyzed by noncondition logistic regression. The risk ratio of the 3 study factors was calculated. Results: Sister chromatid exchange, micronucleus rate, and chromosome structural aberration were important risk factors among the many complicated causes of recurrent apthous ulcer. Conclusion: The results of the study essentially showed that recurrent apthous ulcer patients could have some pathological genetic predisposition and abnormal genetic material.

 

 

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