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Chinese Journal of Dental Research

Year 1999
Volume 2 , Issue 1

Pages: 38 - 44

A Comparison of the Preventive Effects of Lanthanides and Fluoride on Human Experimental Root Surface Carious-Like Lesions


Objective: To investigate the mechanisms of lanthanides prevention of human root surface carious-like lesions and to compare the effectiveness of lanthanum (La) with that of cerium (Ce) and fluoride (F). Various treatment procedures were also compared. Materials and Methods: Acetic buffers containing lanthanum, cerium, and fluoride (500 ppm) were used individually or in combination to treat 48 cementum-dentin samples. The acid-resistant capacity of various treatment procedures was evaluated by means of scanning electron microscope, electron microprobe, and polarizing light microscope analyses. Results: The acid-resistant effects of lanthanide element were comparable to those of fluoride, and their acid-resistant effects were even stronger when combined with fluoride and cerium. These effects are likely due to the formation of La(Ce)HAP, Fla(Ce)HAP, and lanthanum/cerium phosphate compounds. Conclusion: Combined F/La(Ce) was more effective in the prevention of root surface caries than were lanthanides alone.



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