Home Subscription Services
 
   

 
The Chinese Journal of Dental Research
About the Editor
Editorial Board
Author Guidelines
Submission Form
Reprints / Articles
Permissions
Advertising
MEDLINE Search
Official Site
 
 
 
 
 
FacebookTwitterYouTube

Publication:
Chinese Journal of Dental Research

Year 1999
Volume 2 , Issue 1

Back
Pages: 7 - 11

In Vitro and In Vivo Studies of the Effect of a Chinese Herb Medicine on Osteoclastic Bone Resorption

Yu/Chen/Li/Zhang

Objective: To study the effect of a Chinese herb on osteoclastic bone resorption and osteoporosis. Materials and Methods: Osteoclasts were isolated and cultured for in vitro study of the effect of the Chinese herb Guizhou epimedium (Epimedium Leptorrhizum Stearn). The in vivo effect of this Chinese herb was also investigated in rats in whom osteoporosis was induced by ovariectomy; these results were then compared with the effects of estradiol in the same group of rats. Results: The in vitro study showed that the epimedium inhibited the osteoclastic resorption of bone. The in vivo investigation demonstrated that both the epimedium and estradiol were able to increase mineral content and promote bone formation. Conclusion: The Chinese herb Guizhou epimedium is of potential use in the treatment of osteoporosis.

 

 

  © 2014 Quintessence Publishing Co Inc
 

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog