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The Chinese Journal of Dental Research

Edited by Xu Chen MA

Official journal of the Chinese Stomatological Association

ISSN (print) 1462-6446 • ISSN (online) 1867-5646

Publication:

Summer 2013
Volume 16 , Issue 1

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Ghost Cell Differentiation and Calcification in Ameloblastic Fibroma

Luo, Hai Yan / Gao, Yan

Pages: 71-74

Ghost cell differentiation within an ameloblastic fibroma is extremely rare. The ghost cells found in an ameloblastic fibroma in previously reported cases were all associated with a typical calcifying odontogenic cyst. Here, we report a case of an ameloblastic fibroma with focal ghost cells and calcifications in some neoplastic epithelial islands, but without other histologic manifestations consistent with a calcifying odontogenic cyst. The patient was a 13-year-old Chinese boy who presented with a bony-hard swelling in the posterior mandibular region over a 6-month period. Radiographs showed a well-defined multilocular radiolucency associated with an unerupted tooth. The lesion was mostly cystic-solid and comprised of odontogenic epithelial strands, islands and myxoid ectomesenchymal component microscopically. Small groups of ghost cells and calcification were noted in the epithelial islands.

Keywords: ghost cell, ameloblastic fibroma

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