The use of recombinantly engineered growth factors is a significant adjunct for implant surgery. The use of growth factor technology is reducing the need for autogenous bone grafting and allowing for less invasive procedures. The inclusion of tissue engineering in the clinical decision-making process allows the clinician to achieve optimal biologic and esthetic results for challenging periodontal and implant cases. This presentation will provide an update on techniques for esthetic implant site development using recombinant human platelet-derived growth factor BB (rhPDGF-BB). Cases will be presented to demonstrate the successful use of combined rhPDGF-BB and bone replacement grafts to treat extraction socket defects and ridge augmentation procedures in preparation for implant placement. Techniques combining hard and soft tissue grafting for periodontal and implant applications will also be presented. Histologic cores of treated sites will support the clinical results and demonstrate the osteogenic effect of rhPDGF-BB. A pilot study of the use of rhPDGF-BB with mineral collagen bone substitute to treat advanced buccal wall extraction defects will be presented. The initial results demonstrate significant remodeling of xenograft particulate at 4 months posttreatment.
Marc L. Nevins, DMD, MMSc, graduated from Tufts University School of Dental Medicine and received his certificate for graduate training in periodontology and a masterís degree in oral biology at Harvard School of Dental Medicine. Dr Nevins is in private practice specializing in periodontics and implant dentistry in Boston, Massachusetts. He is a diplomate of the American Board of Periodontology and is an assistant clinical professor in the Division of Periodontology, Department of Oral Medicine, Infection and Immunity at Harvard School of Dental Medicine. Dr Nevins is the associate editor of The International Journal of Periodontics & Restorative Dentistry. His research interests are clinical applications of tissue engineering for periodontics and implant dentistry.
Approximate Running Time: 45 minutes