The goal of regenerative periodontal therapy is the reconstitution of the lost periodontal structures (formation of new cementum, periodontal ligament, and alveolar bone). Results from preclinical and clinical studies have pointed to the important role of an enamel matrix protein derivative (EMD) in periodontal wound healing. Animal and human histologic studies have provided evidence that treatment with EMD may indeed promote periodontal regeneration, while clinical studies have indicated that surgical treatment with EMD may bear clinical relevance in intrabony, Class II furcation- and recession-type defects. This lecture will review the existing evidence on the effects of EMD on periodontal wound healing and regeneration and draw clinically relevant conclusions.
Anton Sculean, DMD, MS, PhD, studied dentistry at the Semmelweis University, Budapest, Hungary, and received postgraduate training in periodontology in Münster, Germany, and at the Royal Dental College, Aarhus, Denmark. Recognized as a specialist of the German Society of Periodontology, Dr Sculean earned his doctorate at the University of Homburg, Germany. He has served as head of the Section of Periodontology at the University of Mainz, Germany, and as head of the Department of Periodontology and director of the postgraduate program in periodontology at Radboud University, Nijmegen, The Netherlands. His research interests are periodontal wound healing and regeneration, clinical trials on reconstructive periodontal therapy, and oral biofilms. Dr Sculean has authored or co-authored more than 150 publications in peer-reviewed journals, contributed 12 chapters to textbooks, and presented more than 180 lectures at national and international meetings.
Approximate Running Time: 60 minutes