Periodontal maintenance therapy, as defined by longitudinal studies from throughout the world, provides outstanding clinical outcomes, as assessed by mean quantitative clinical parameters. Yet the average outcomes for maintenance patients do not reflect the fact that a subgroup of patients continues to lose teeth and exhibit generalized progressive disease. Patients’ failure to adhere to maintenance regimens is one factor in outcomes. There is, however, evidence to suggest that other factors contribute to unfavorable outcomes during maintenance therapy and that therapeutic outcomes may be more predictable than current standards in practice. This presentation will examine the evidence for two dramatically different outcomes of maintenance therapy. It will also consider the major risk factors that have been implicated in different treatment responses, including smoking, diabetes, and genetic variations, as well as some of the novel risk factors that are emerging. This presentation will also provide some context as to how such information may be used in the future by insurance companies and government entities that are considering comparative effectiveness in health care.
Kenneth S. Kornman, DDS, MS, PhD, is the chief scientific officer at Interleukin Genetics, a biotechnology company focused on genetic variations that influence inflammatory mechanisms and chronic diseases. Dr Kornman is actively involved in functional genomics research and gene-environment interactions relative to common diseases of aging. He has published more than 100 manuscripts and authored three textbooks on treatment of periodontal disease. Dr Kornman is on the editorial board of several journals and is editor-in-chief of the Journal of Periodontology. He was previously professor and chairman of the Department of Periodontics and a professor of microbiology at the University of Texas Health Science Center at San Antonio; a visiting professor in the School of Engineering at Stanford University; and currently retains an academic appointment at Harvard University. Dr Kornman holds more than 20 US patents on gene variations that regulate chronic diseases and on software methods for modeling complex biologic mechanisms.
Approximate Running Time: 45 minutes